Anastasia Romanovna Zakharyina-Yurieva (1530 – August 7, 1560) was the first wife of the Russian Tsar Ivan the Terrible and the first Russian tsaritsa. She was the daughter of Boyar Roman Yurievich Zakharyin-Yuriev, Okolnichi, who died on 16 February 1543, who gave his name to the Romanov Dynasty of Russian monarchs, and wife Uliana Ivanovna, who died in 1579.